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Updated: Feb 1, 2026

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Detection of Tetracycline in Water Using Glutathione-protected Fluorescent Gold Nanoclusters
Dongri Liu1, Xiaoyi Pan1, Wei Mu1
1State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology.
Abstract:
Tetracycline (Tc), a widely used antibiotic, is one of the major pollutants in water. Herein, glutathione (GSH)-protected Au nanoclusters (GSH-AuNCs) were prepared to detect Tc. The fluorescence quenching ratio of GSH-AuNCs shows an excellent linear response against tetracycline in the concentration range of 50 μg/L - 50 mg/L with the detection limit of 5.31 μg/L. For the test paper prepared by GSH-AuNCs, 1 mg/L Tc caused a significant difference that could be recognized by the naked eye. The method exhibited good selectivity and excellent recovery when applied to a tap water sample. The method has the potential for Tc detection in real samples.
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