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Updated: Feb 1, 2026
07:00
A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
Published on: October 5, 2018
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[Glaucoma due to elevated episcleral venous pressure]
R Greslechner1, I Oberacher-Velten2,3
1Klinik und Poliklinik für Augenheilkunde, Klinikum der Universität Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland. greslechner@eye-regensburg.de.
Summary
Glaucoma from elevated episcleral venous pressure is rare but challenging to treat. Early diagnosis and management of underlying conditions are crucial due to high complication risks.
Area of Science:
- Ophthalmology
- Glaucoma Research
Background:
- Elevated episcleral venous pressure causes a rare form of secondary open-angle glaucoma.
- This condition presents significant diagnostic and therapeutic challenges.
Purpose of the Study:
- To review the pathophysiology, clinical presentation, differential diagnosis, and treatment of glaucoma due to elevated episcleral venous pressure.
- To highlight specific conditions such as Radius-Maumenee syndrome, Sturge-Weber syndrome, and carotid-cavernous sinus fistulas.
Main Methods:
- A comprehensive literature search was performed using the PubMed database.
Main Results:
- Diagnostic workup must exclude serious conditions like carotid-cavernous sinus fistulas.
- Treatment focuses on the underlying cause; medical therapy is often inadequate.
- Surgical interventions carry a high risk of severe complications, with varied approaches reported in limited case series.
Conclusions:
- Glaucoma secondary to elevated episcleral venous pressure can be idiopathic or linked to other diseases.
- Despite its rarity, it warrants consideration in differential diagnoses.
- Treatment is complex due to the elevated risk of significant complications.
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