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Related Concept Videos

Coordination Number and Geometry02:57

Coordination Number and Geometry

19.0K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
19.0K
Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

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In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
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Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

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The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
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DNA-only Transposons02:57

DNA-only Transposons

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DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
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What is Genetic Engineering?00:49

What is Genetic Engineering?

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Overview
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Hybrid Zones02:29

Hybrid Zones

21.9K
Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.
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Related Experiment Video

Updated: Feb 1, 2026

Improving the Combustion Performance of a Hybrid Rocket Engine using a Novel Fuel Grain with a Nested Helical Structure
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Improving the Combustion Performance of a Hybrid Rocket Engine using a Novel Fuel Grain with a Nested Helical Structure

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Engineering Multifunctional DNA Hybrid Nanospheres through Coordination-Driven Self-Assembly.

Mengyuan Li1,2, Congli Wang1,3, Zhenghan Di1,3

  • 1CAS Key Laboratory for Biomedical Effects of Nanomaterials, and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190, China.

Angewandte Chemie (International Ed. in English)
|December 4, 2018
PubMed
Summary

Researchers developed a new method to create precise Fe-DNA nanospheres using metal ion coordination. These DNA-based nanomaterials show potential for enhanced cellular delivery and advanced DNA nanobiotechnology applications.

Keywords:
DNA nanobiotechnologycoordination polymerhybrid materialsnanomedicineself-assembly

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A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
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A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
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Area of Science:

  • Nanotechnology
  • Biotechnology
  • Coordination Chemistry

Background:

  • Developing DNA nanomaterials with controlled morphology and function is crucial for diverse applications.
  • Existing synthesis methods may lack simplicity or generality.

Purpose of the Study:

  • To report a novel approach for synthesizing DNA-based nanoarchitectures using coordination-driven self-assembly.
  • To demonstrate the precise control over size and composition of these Fe-DNA nanostructures.

Main Methods:

  • Coordination-driven self-assembly of iron(II) ions and DNA molecules.
  • Fine-tuning assembly parameters to control nanosphere characteristics.

Main Results:

  • Successful synthesis of a new set of DNA-based nanoarchitectures (Fe-DNA nanospheres).
  • Precise control over the size and composition of the hybrid nanoparticles was achieved.
  • Demonstrated tailored nanoparticles for enhanced delivery of functional DNA in vitro and in vivo.

Conclusions:

  • Metal ion coordination is a viable strategy for directing DNA architecture assembly.
  • This methodology expands the range of DNA-based nanomaterials.
  • Advances DNA nanobiotechnology and metal-ligand coordination chemistry.