Related Experiment Video
Updated: Feb 1, 2026

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
Published on: December 13, 2016
Cation-π Interactions in Organic Synthesis
1Department of Chemistry, Faculty of Science , Ochanomizu University , 2-1-1 Otsuka , Bunkyo-ku , Tokyo 112-8610 , Japan.
Abstract:
The cation-π interaction is an attractive noncovalent interaction between a cation and a π system. Due to the stronger interaction energy than those of the other π interactions, such as π-π and CH-π interactions, the cation-π interaction has recently been recognized as a new tool for controlling the regio- and stereoselectivities in various types of organic reactions. This review attempts to cover a variety of organic reactions controlled by cation-π interactions, which includes not only recent examples but also those reported before the term "cation-π interaction" was defined in 1990. This review will provide comprehensive knowledge on the role of cation-π interactions in organic synthesis.
More Related Videos
Related Concept Videos
π Molecular Orbitals of the Allyl Cation and Anion
Synthesis and Decomposition Reactions
π Molecular Orbitals of 1,3-Butadiene
The simplest conjugated diene is 1,3-butadiene: a four-carbon system where each carbon is sp2-hybridized and has an unhybridized p orbital that contains an unpaired electron. According to molecular orbital theory, atomic orbitals combine to form molecular orbitals such that the number...
Levels of Organization
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
Dehydration Synthesis
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...
π Electron Effects on Chemical Shift: Overview

