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Updated: Feb 1, 2026

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of ManganeseII Acetylacetonate
Published on: June 18, 2020
Sustainable Alkylation of Unactivated Esters and Amides with Alcohols Enabled by Manganese Catalysis
Yoon Kyung Jang1, Tobias Krückel1, Magnus Rueping1,2
1Institute of Organic Chemistry , RWTH Aachen University , Landoltweg 1 , 52074 Aachen , Germany.
Abstract:
The first example of manganese-catalyzed C-alkylation of the carboxylic acid derivatives is reported. The bench-stable homogeneous manganese complex enables the transformation of the renewable alcohol and carboxylic acid derivative feedstock to higher value esters and amides. The reaction operates via hydrogen autotransfer and ideally produces water as the only side product. Importantly, aliphatic-, benzylic-, and heterocyclic-containing alcohols can be used as alkylating reagents, eliminating the need for mutagenic alkyl halides.
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