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Updated: Feb 1, 2026

Development of a Noninvasive, Laser-Assisted Experimental Model of Corneal Endothelial Cell Loss
Published on: April 24, 2020
Corneal endothelial cell loss associated to phacoemulsification and ophthalmologist experience: prospective analysis
Fernando Chamorro1, Cristóbal Briones2, Cristóbal Loézar3
1Escuela de Medicina, Facultad de Medicina, Universidad de Valparaíso, Chile. Address: Facultad de Medicina, Universidad de Valparaíso, Angamos 655, Viña del Mar, Chile.
Introduction:
Phacoeresis is the procedure through which the lens is surgically removed to treat cataracts. A corneal endothelial loss is a recognized sequel. Although several factors associated with this harm have been described, the surgeons prior experience has been scarcely evaluated.
Objectives:
To assess the association between the surgeons experience and other variables associated with a corneal endothelial cell loss in the context of phacoeresis.
Methods:
Clinical records of 198 patients undergoing cataract operations were prospectively reviewed. The experience of the surgeon and other variables were recorded, including cumulative dissipated energy, viscoelastic type, the use of trypan blue, amount of fluidics, ultrasound time, combined phacoemulsification energy, and pre- and postoperative corneal endothelial cell counts.
Results:
No differences were observed in the postoperative corneal endothelial cell count between surgeons with more or less than five years of experience. Nevertheless, ophthalmologists with more than five years experience used less trypan blue, but more cumulative dissipated energy in each procedure, while less experienced ophthalmologists used less fluidics.
Conclusions:
Although there were differences in the surgical management regarding the surgeons experience in factors known to influence corneal endothelial cell loss, no differences in endothelial cell loss were observed as an outcome.
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