Related Experiment Video
Updated: Feb 1, 2026

Biaxial Mechanical Characterizations of Atrioventricular Heart Valves
Published on: April 9, 2019
[Heart Valve Disease - update ESC guideline 2017]
1Universitäres Herzzentrum, Zentrum für Innere Medizin, Abteilung für Kardiologie an der Universitätsmedizin Rostock und Klinik für Innere Medizin - Kardiologie und konservative Intensivmedizin am Vivantes Klinikum im Friedrichshain und Vivantes Klinikum Am Urban, Berlin.
Transcatheter aortic valve implantation (TAVI) offers comparable results to surgery for aortic stenosis. The Heart Team approach is crucial for individualized care in complex valvular heart disease.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Surgical management for aortic valve stenosis is decreasing, with transcatheter aortic valve implantation (TAVI) emerging as a preferred treatment.
- Mitral regurgitation (MR) presents challenges, particularly secondary MR linked to left ventricular disease, where edge-to-edge repair (Mitraclip) is an option for high-risk patients.
- Guidelines now incorporate randomized controlled trials for intermediate-risk patients undergoing TAVI, showing comparable outcomes to surgical approaches.
Purpose of the Study:
- To update recommendations on the management of valvular heart disease, including aortic stenosis and mitral regurgitation.
- To emphasize the importance of the Heart Team approach in managing complex cardiac valve conditions.
- To outline requirements for heart valve centers ensuring individualized patient care.
Main Methods:
- Integration of results from randomized controlled trials into clinical guidelines.
- Evaluation of interventional (Mitraclip) and surgical treatment options for mitral regurgitation.
- Assessment of recommendations for treating concomitant coronary artery disease in patients with valvular heart disease.
Main Results:
- Transcatheter aortic valve implantation (TAVI) demonstrates good and comparable results to traditional surgical methods for aortic stenosis.
- Edge-to-edge mitral valve repair (Mitraclip) provides an alternative for high-risk patients with secondary mitral regurgitation.
- Treatment of proximal coronary artery stenosis (≥70%) is recommended before TAVI or concurrently with valve surgery.
Conclusions:
- The Heart Team, comprising cardiologists, cardiac surgeons, and other specialists, is essential for optimal, individualized patient care.
- Increasing therapeutic options necessitate a multidisciplinary approach for managing valvular heart disease.
- Established requirements for heart valve centers aim to ensure excellent patient outcomes.
Related Concept Videos
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Rheumatic Heart Disease I: Introduction
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Anatomy of the Heart
Rheumatic Heart Disease III: Medical Management
Rheumatic Heart Disease IV: Nursing Management

