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Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
A case report on middle cerebral artery aneurysm treated by rapid ventricular pacing: A CARE compliant case report
1Department of Anesthesiology, Huashan Hospital Fudan University, Shanghai, China.
Insights
Rapid ventricular pacing (RVP) effectively reduces blood pressure during cerebral aneurysm surgery, lowering risks of rupture and hemorrhage. This method provides a safe window for clipping aneurysms, improving patient outcomes.
Area of Science:
- Neurosurgery
- Cardiovascular Physiology
- Medical Technology
Background:
- Cerebral aneurysms are a leading cause of stroke and death, often treated with invasive surgery.
- Surgical risks include aneurysm rupture, leading to severe neurological damage or mortality.
- Rapid ventricular pacing (RVP) is a technique to transiently lower blood pressure by increasing heart rate.
Observation:
- A 46-year-old patient presented with chronic headaches and recent neurological deficits.
- Diagnostic imaging confirmed a large right middle cerebral artery (MCA) aneurysm.
- RVP was employed during surgical repair to mitigate procedural risks.
Findings:
- The patient underwent successful MCA aneurysm repair with RVP.
- Post-procedure imaging showed no residual aneurysm or complications.
- Neurological function improved, with motor strength grading V on the right and IV on the left extremities at seven weeks.
Implications:
- RVP offers a safe and effective strategy for transiently reducing cardiac output in intracranial aneurysm surgery.
- This technique can create a critical "low pressure" state, facilitating safer aneurysm clipping, especially in rupture scenarios.
- RVP may improve surgical safety and reduce the risk of catastrophic outcomes in complex cerebrovascular procedures.
Rationale:
Cerebral aneurysm is a common cause of intracranial hemorrhage, stroke, and death. It is treated with vascular surgeries, such as coil embolism and artery clipping. However, surgery itself is a risk factor that may cause rupture of aneurysm, and leads to irreversible brain damage, and even death. Rapid ventricular pacing (RVP) is a procedure that temporarily lowers blood pressure by increasing heart rate and reducing ventricular filling time. RVP has been widely used to reduce blood vessel tension in many cardiovascular surgeries.
Patient Concerns:
A 46-year-old man came to our hospital with intermittent right-side headache for 5 years, and left lower limb numbness for 3 months.
Diagnoses:
Magnetic resonance imaging (MRI) of the head and digital subtraction angiography confirmed the diagnosis of right middle cerebral artery (MCA) aneurysm.
Interventions:
Considering the large size of this MCA aneurysm, RVP was used to reduce blood pressure during MCA aneurysm repair, and to lower the risk of intracranial hemorrhage during procedure.
Outcomes:
Post procedure, there was no abnormality detected. Seven weeks after surgery, the patient's muscle tone of right side extremities were grade V and left side extremities were grade IV. Computed tomography angiography confirmed no MCA aneurysm.
Lessons:
In cases of aneurysm rupture, RVP will induce a transient "very low pressure" condition, and give a valuable time frame to clip the ruptured aneurysm. Therefore RVP is a safe and effective method to provide transient reduction of cardiac output in intracranial aneurysm patients.
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