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Updated: Feb 1, 2026

Microstate and Omega Complexity Analyses of the Resting-state Electroencephalography
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Dimensional Complexity of the Resting Brain in Healthy Aging, Using a Normalized MPSE

Norman Scheel1,2,3, Eric Franke1, Thomas F Münte2

  • 1Institute for Neuro- and Bioinformatics, Universität zu Lübeck, Lübeck, Germany.

Frontiers in Human Neuroscience
|December 5, 2018
PubMed
Summary

This study introduces normalized Multivariate Principal Subspace Entropy (nMPSE) to analyze brain activity complexity using functional MRI. The new method reveals age-related changes in brain regions, offering potential for biomarker discovery.

Keywords:
Rockland samplecomplexitydimensional complexityentropyfunctional magnetic resonance imaging (fMRI)healthy agingprincipal subspace analysis (PSA)resting-state fMRI

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