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Saccade-based termination responses in macaque V1 and visual perception.

James E Niemeyer1, Michael A Paradiso1

  • 1Department of Neuroscience,Brown University,Providence,Rhode Island.

Visual Neuroscience
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PubMed
Summary
This summary is machine-generated.

Neurons in the visual cortex exhibit termination responses when stimuli disappear, even during natural eye movements. These responses, influenced by both visual and nonvisual cues, may relate to saccadic suppression.

Keywords:
After-dischargeNatural visionOff effectPrimary visual cortexSaccadic suppression

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Area of Science:

  • Neuroscience
  • Visual processing
  • Sensory perception

Background:

  • Neurons in visual cortex typically increase firing when a stimulus appears in their receptive field (RF).
  • Neurons also show "termination responses" when a stimulus disappears, observed in area V1 and potentially influencing visual perception.
  • The role of these responses during naturalistic vision, particularly with eye movements, is less understood.

Purpose of the Study:

  • To investigate the strength of neuronal termination responses in the primary visual cortex (V1) during naturalistic stimulus removal caused by eye movements (saccades).
  • To compare termination responses elicited by saccadic eye movements with those elicited by flashed-off stimuli.
  • To explore the potential contribution of nonvisual signals to termination responses.

Main Methods:

  • Electrophysiological recordings were performed in the primary visual cortex (V1) of macaque monkeys.
  • Stimuli were presented and then removed from the receptive field (RF) either by flashing them off or by using saccadic eye movements to shift the RF.
  • Neuronal firing rates were analyzed to quantify the presence and amplitude of termination responses.

Main Results:

  • Termination responses were observed in macaque V1 when stimulus removal was caused by saccadic eye movements.
  • These saccade-elicited termination responses were smaller in amplitude compared to responses evoked by stimuli that were simply flashed off.
  • Termination responses were also detected in the absence of any visual stimulation, suggesting nonvisual influences.

Conclusions:

  • Termination responses are a component of naturalistic vision, occurring during eye movements.
  • These responses are influenced by both visual input and nonvisual signals within the visual cortex.
  • The reduced amplitude of termination responses during saccades might be a neural basis for saccadic suppression, the diminished perception during eye movements.