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Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

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Updated: Feb 1, 2026

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Published on: May 20, 2016

Epilepsy surgery

Francine Chassoux¹, Bertrand Devaux¹

¹Service de neurochirurgie, centre hospitalier Sainte-Anne, université Paris-Descartes Paris, France.

La Revue Du Praticien

|December 5, 2018

Summary

This summary is machine-generated.

Epilepsy surgery offers a drug-resistant epilepsy solution for children and adults. This treatment provides long-term seizure freedom in 60-80% of patients, improving quality of life.

Keywords:

Neurochirurgie Épilepsie

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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Area of Science:

Neurosurgery
Epileptology

Background:

Epilepsy surgery has advanced significantly due to improved candidate selection, imaging, and surgical techniques.
Key indications include temporal lobe epilepsy with hippocampal sclerosis, low-grade glial tumors, and focal cortical dysplasia.

Purpose of the Study:

To review the indications, assessment methods, surgical procedures, and outcomes of epilepsy surgery.
To highlight the benefits of epilepsy surgery in terms of seizure control, quality of life, and cost reduction.

Main Methods:

Pre-surgical assessment involves clinical, neurophysiological, and imaging data.
Neuropsychological and psychiatric evaluations are crucial for assessing comorbidities and risks.
Stereo-electroencephalography (SEEG) may be used for precise epileptogenic zone localization.

Main Results:

Resection surgery (corticectomy or lesionectomy) is the most common procedure.
Seizure-free outcomes are achieved in 60-80% of patients post-surgery with low morbidity.
Long-term results show sustained seizure freedom, improved quality of life, and reduced disease costs.

Conclusions:

Epilepsy surgery is a viable and effective treatment for drug-resistant epilepsy.
Optimal outcomes are associated with younger patients and shorter epilepsy duration.