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Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay
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Evolution Repeats Itself in Building a Species Barrier
Madhav Jagannathan1, Yukiko Yamashita2
1Life Sciences Institute, Ann Arbor, Michigan, USA.
Developmental Cell
|December 5, 2018
Abstract:
Exploring the mechanisms that cause hybrid incompatibility can illuminate divergent genomic elements between species that may otherwise be cryptic. Recent work shows that uniparental chromosome elimination in hybrids between two frog species triggers a metabolic crisis and embryonic lethality.
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