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Updated: Feb 1, 2026

Decellularization and Recellularization Methodology for Human Saphenous Veins
Published on: July 27, 2018
Reinventing the Saphenous Vein: Reconstructing the Anterior Mitral Leaflet With a Saphenous Vein
Jacques T Janson1, Alfonso Pecoraro2
1Division of Cardiothoracic Surgery, Stellenbosch University, Tygerberg, South Africa.
Abstract:
Mitral valve repair can sometimes require leaflet augmentation or a patch repair of a defect in the leaflet. No ideal patch material is currently available that can grow and adapt to the mitral leaflet. This report describes a new technique using autologous saphenous vein as patch material. The saphenous vein is untreated, living tissue and remains flexible as a patch or leaflet augmentation for up to 3 years on echocardiography.
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