Potentiometric characterization of iodine-based disinfecting preparations
Waldemar Gottardi1, Markus Nagl1
1Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Abstract:
A potentiometric method is presented that allows to characterize aqueous iodine-based disinfecting solutions and preparations, respectively. By means of three electrodes (iodide-sensitive, platinum redox, and reference electrode), the concentrations of free iodine, iodide, and triiodide were determined. The apposition "free" means iodine not complexed with ligands originating from the organic matrix of the iodophoric iodine source (e.g. povidone iodine). Based on the gained values ([I2], [I-], and[I3-]), it is possible to assess features concerning kinetics of disinfection, disinfecting capacity, and tolerability. The method distinguishes by simplicity and modest time expenditure of 10-15 min for a complete investigation comprising two potentiometric measurements.
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