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Selected Risk Factors of Developmental Delay in Polish Infants: A Case-Control Study
Marzena Drozd-Dąbrowska1, Renata Trusewicz2, Maria Ganczak3
1Department of Epidemiology and Management, Pomeranian Medical University, 71-210 Szczecin, Poland. mdrozd@pum.edu.pl.
Insights
Identifying risk factors for developmental delay (DD) in Polish infants is crucial for early diagnosis and prevention. This study highlights maternal infections, Caesarian birth, and low birth weight as key risk factors for DD in infants.
Area of Science:
- Pediatrics
- Neonatology
- Public Health
Background:
- Developmental delay (DD) poses a significant challenge in pediatric care.
- Limited data exists on DD risk factors in Polish infants, hindering timely interventions.
- Early identification of risk factors is essential for effective prevention and management strategies.
Purpose of the Study:
- To investigate and identify selected risk factors associated with developmental delay in infants in Poland.
- To provide data that can inform early diagnosis and prevention programs for DD in the Polish population.
Main Methods:
- A case-control study involving 50 infants (≤1 year) with DD and 104 healthy controls.
- Data collection through anonymous questionnaires administered to mothers in Szczecin, Poland (2017-2018).
- Statistical analysis to determine significant correlations between risk factors and DD.
Main Results:
- Common risk factors identified in infants with DD include Caesarian section (68%), infections (46%), and maternal chronic diseases (48%).
- Significant correlations found between DD and maternal infections/chronic diseases, Caesarian section, preterm birth, low birth weight (<2500g), low Apgar score (≤7), prolonged hyperbilirubinemia, and lack of breastfeeding.
- The study confirms the multifactorial etiology of developmental delay.
Conclusions:
- Preventive strategies for infant DD in Poland must address identified pre/peri/postnatal risk factors.
- Early detection and intervention in high-risk infants are highly recommended.
- The findings underscore the need for targeted public health initiatives to mitigate DD risks.
Abstract:
Despite a number of studies on the risk factors of developmental delay (DD) in children conducted in developed countries, Polish data are scarce, which hinder an early diagnosis and initiation of prevention/control measures. Objective: To assess selected risk factors of DD in infants. A case-control survey was conducted in 2017⁻2018 on 50 infants (≤1 year old) with DD and 104 healthy controls from three outpatient clinics in Szczecin, Poland. Data were collected using an anonymous questionnaire distributed among mothers. The most common risk factors in infants with DD were: Caesarian section (68%), infections (46%), and chronic diseases during pregnancy (48%). DD was significantly correlated with maternal infections and chronic diseases during pregnancy (both: p < 0.001), caesarian section (p < 0.001), preterm birth (p = 0.004), birth weight <2500 g (p = 0.03), Apgar score ≤7 (p < 0.01), prolonged hyperbilirubinemia (p < 0.001), and no breast-feeding (p = 0.04). This study reinforces multiple etiologies of DD. Preventive strategies regarding DD in Polish infants should focus on the pre/peri/postnatal risk factors identified in this study. Strategies that prevent and control such risk factors and those on early detection and intervention in high-risk infants are highly recommended.
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