Related Experiment Video
Updated: Feb 1, 2026

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
Published on: October 2, 2018
Treatment of caffeine toxicity with metoprolol
Siu Fai Li1, Lindsey Edwards1, Vincent Nguyen1
1Department of Emergency Medicine, Jacobi Medical Center, Bronx, NY, United States of America.
Abstract:
A 27-year-old man presented with an intentional overdose of concentrated caffeine powder that he bought over the internet. The patient received benzodiazepines and ondansetron for symptomatic treatment when he arrived in the Emergency Department (ED). Subsequently, he developed recurrent supraventricular tachycardia in the ED. The SVT was successfully treated with metoprolol. The patient's caffeine level was >90 mg/L. This is the first known report of treatment of caffeine-induced supraventricular tachycardia with metoprolol.
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