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Evaluating the Association Between the Three Different Ejection Fraction Measurement Techniques and Left Ventricle
Ednan Bayram1, Oktay Gulcu2, Ugur Aksu3
1Department of Cardiology, Atatürk University School of Medicine, Erzurum, Turkey.
Insights
The Simpson
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Imaging
Background:
- Cardiovascular disease (CVD) prognosis relies on systolic function, measured by ejection fraction (EF).
- Left ventricular global strain (LVGS) shows superior predictivity for CVD diagnosis, prognosis, and staging compared to EF.
- Previous studies have not thoroughly investigated the correlation between different EF measurement methods and LVGS parameters.
Purpose of the Study:
- To analyze the association between three ejection fraction (EF) measurement methods and left ventricular global strain (LVGS).
- To determine which EF measurement method correlates best with LVGS.
- To evaluate the diagnostic utility of different EF methods for abnormal LVGS.
Main Methods:
- Echocardiography was performed on 62 patients (excluding those with atrial fibrillation or poor image quality).
- Three EF measurement techniques were employed: visual EF, Simpson's rule EF, and Teicholtz method.
- Statistical analysis was used to assess the correlation between EF measurements and LVGS parameters.
Main Results:
- A statistically significant association was found between visual EF, Simpson EF, and LVGS parameters (p<0.001).
- Simpson's rule EF demonstrated a good correlation with LVGS parameters (r=0.710).
- Visual EF showed a moderate correlation with LVGS parameters (r=0.44).
Conclusions:
- Simpson's rule ejection fraction (EF) measurement correlates better with left ventricular global strain (LVGS) than visual EF or the Teicholtz method.
- Simpson's rule EF offers a superior area under the curve for identifying abnormal LVGS.
- The study recommends using Simpson's rule EF for evaluating ventricular function due to its stronger correlation with LVGS.
Objective:
The prognosis of cardiovascular diseases (CVDs) is directly associated with systolic function based on the measurement of ejection fraction (EF), and many studies have indicated that the left ventricular global strain (LVGS) provides better predictivity than the EF measurement in the diagnosis, prognosis, survival, and CVD staging. However, these studies did not investigate the correlation between the EF measurement and the LVGS parameters, or which parameters are better correlated with LVGS, but we analyzed the association between three EF measurement methods and LVGS.
Materials And Methods:
This study included 62 patients that applied to the clinic between October 2015 and March 2016. An echocardiography examination of these patients was performed. The exclusion criteria were atrial fibrillation and suboptimal image quality.
Results:
Sixty-two patients (the average age 61.0±12.6 years; 56% male and 44% female) were enrolled in the study. A statistically significant association was found between the visual EF and Simpson EF measurements and the LVGS parameters (p<0.001). While the visual EF was moderately correlated with the LVGS parameters (r=0.44), there was a good correlation between the Simpson EF and the LVGS parameters (r=0.710).
Conclusion:
In this study, we demonstrate that the Simpson's rule LVEF correlates better with LVGS than the Teicholtz method or visual EF and that it has a better area under the curve value for determining an abnormal LVGS. Therefore, we recommend the use of the Simpson EF for the EF measurement that has a better correlation with the LVGS values in the patients whose ventricle functions should be evaluated.
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