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Updated: Feb 1, 2026

Generation and Characterization of Rat Uterus Organoids from Rat Endometrial Epithelial Stem Cells
Published on: August 2, 2024
Stem Cells and Endometrial Regeneration: From Basic Research to Clinical Trial
Xinxin Zhu1, Bruno Péault2, Guijun Yan3
1Center for Reproductive Medicine, Drum Tower Clinic Medical College of Nanjing Medical University, Nanjing 210029, Jiangsu, China.
Abstract:
Monthly changes in the endometrial cycle indicate the presence of endometrial stem cells. In recent years, various stem cells that exist in the endometrium have been identified and characterized. Additionally, many studies have shown that Bone Marrow Mesenchymal Stem Cells (BM-MSCs) provide an alternative source for regenerating the endometrium and repairing endometrial injury. This review discusses the origin of endometrial stem cells, the characteristics and main biomarkers among five types of putative endometrial stem cells, applications of endometrium-derived stem cells and menstrual blood-derived stem cells, the association between BM-MSCs and endometrial stem cells, and progress in repairing endometrial injury.
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