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Updated: Feb 1, 2026

Meiotic Spindle Assessment in Mouse Oocytes by siRNA-mediated Silencing
Published on: October 11, 2015
Does the meiotic spindle really predicts embryo implantation and live birth rates? An update
Sabela García-Oro1, Diana Valverde2
11Equipo Ron - Hospital Quironsalud A Coruña,C/Londres 2, 15009 A Coruña,Spain.
Abstract:
SummaryThe aim of this study was to determine the capacity of the meiotic spindle (MS) to predict embryo implantation and live birth rates. For this purpose, we performed a broad systematic literature search. Of all publications retrieved, only those in which the implantation rates were related to some characteristics of the MS were evaluated. Despite the different methodology used in all the chosen studies, presence of the MS in oocytes was found to be positively associated with embryo implantation. Moreover, high retardance values, as well as strict criteria of normality in the MS structure, are significantly related to higher embryo implantation numbers and live birth rates.
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