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Juvenile Nasal Angiofibroma on 68Ga-PSMA PET/CT: Opening New Frontiers
Pirabu Sakthivel1, Arun Prashanth2, Alok Thakar1
1From the Departments of Otorhinolaryngology and Head and Neck Surgery, and.
Abstract:
The prostate-specific membrane antigen (PSMA) is highly expressed in prostatic cancer. However, PSMA expression is also noted in various benign and malignant nonprostatic neoplasms in the endothelial cells of tumor-associated neovasculature. We performed Ga-PSMA PET/CT in a 14-year-old boy with juvenile nasal angiofibroma (JNA) to explore its theranostic potential. The scan revealed high uptake in the lesion. Performance of PSMA PET/CT in JNA opens up new frontiers with respect to radiological staging, early recurrence identification, and perhaps even radioligand therapy of residual/recurrent JNAs in the future.
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