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Updated: Feb 1, 2026

Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization
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Monoclonal anti-CD47 interference in red cell and platelet testing.

Randall W Velliquette1, Judith Aeschlimann1, Julie Kirkegaard1

  • 1Immunohematology and Genomics Laboratory, New York Blood Center, New York, New York; and the Community Blood Center, Kansas City, Missouri.

Transfusion
|December 6, 2018
PubMed
Summary

Anti-CD47 antibody interferes with blood transfusion testing, causing false positives. Multiple red blood cell adsorptions or specific anti-IgG reagents are needed to mitigate this interference.

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