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Related Concept Videos

Quantum Numbers02:43

Quantum Numbers

50.1K
It is said that the energy of an electron in an atom is quantized; that is, it can be equal only to certain specific values and can jump from one energy level to another but not transition smoothly or stay between these levels.
50.1K
The Quantum-Mechanical Model of an Atom02:45

The Quantum-Mechanical Model of an Atom

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Shortly after de Broglie published his ideas that the electron in a hydrogen atom could be better thought of as being a circular standing wave instead of a particle moving in quantized circular orbits, Erwin Schrödinger extended de Broglie’s work by deriving what is now known as the Schrödinger equation. When Schrödinger applied his equation to hydrogen-like atoms, he was able to reproduce Bohr’s expression for the energy and, thus, the Rydberg formula governing hydrogen spectra.
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Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism01:21

Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism

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Polymorphism refers to the existence of a drug substance in multiple crystalline forms, known as polymorphs. Recently, this term has been expanded to include solvates (forms containing a solvent), amorphous forms (non-crystalline forms), and desolvated solvates (forms from which the solvent has been removed).
Some polymorphic crystals possess lower aqueous solubility than their amorphous counterparts, leading to incomplete absorption. For instance, the oral suspension of Chloramphenicol, which...
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2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)01:19

2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)

1.4K
Heteronuclear single-quantum correlation spectroscopy (HSQC) is a 2D NMR technique that reveals one-bond correlations between hydrogen and a heteronucleus. The HSQC experiment is similar to the heteronuclear correlation experiment (HETCOR) but is more sensitive. In the HSQC spectrum, the proton chemical shift is plotted on the horizontal F2 axis, while the 13C chemical shift is plotted on the vertical F1 axis. The corresponding proton and 13C spectra are also shown. The HSQC contour plot does...
1.4K
The Pauli Exclusion Principle03:06

The Pauli Exclusion Principle

59.3K
The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information:
59.3K
Structures of Solids02:22

Structures of Solids

17.7K
Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
17.7K

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Updated: Feb 1, 2026

Biofunctionalization of Magnetic Nanomaterials
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Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

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Amorphous Quantum Nanomaterials.

Ferdinand F E Kohle1,2, Joshua A Hinckley1,2, Songying Li1

  • 1Department of Materials Science and Engineering, Cornell University, Ithaca, NY, 14853, USA.

Advanced Materials (Deerfield Beach, Fla.)
|December 6, 2018
PubMed
Summary
This summary is machine-generated.

Disordered glassy materials offer new ways to control quantum materials. By isolating dyes in silica nanoparticles, researchers tuned quantum behavior for advanced imaging and therapy, enabling clinical translation.

Keywords:
amorphous silica nanoparticlesoptical super-resolution microscopyorganic dyesphotodynamic therapy (PDT)

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Area of Science:

  • Quantum materials science
  • Nanotechnology
  • Spectroscopy

Background:

  • Macroscopic quantum material behavior typically relies on crystalline solids.
  • Disordered materials offer alternative approaches to control quantum properties.

Purpose of the Study:

  • To demonstrate the use of disordered glassy materials for tailoring quantum material properties.
  • To develop efficient nanoprobes for photodynamic therapy (PDT) and stochastic optical reconstruction microscopy (STORM).

Main Methods:

  • Isolating single dye molecules in amorphous silica nanoparticles (<10 nm).
  • Chemically tuning the local silica environment to control dye quantum behavior.
  • Utilizing principles from single-molecule spectroscopy.

Main Results:

  • Demonstrated exquisite control over dye quantum behavior by tuning the amorphous silica environment.
  • Developed efficient nanoprobes for PDT and STORM.
  • Showcased fine-tuning of light-induced quantum behavior via spin-orbit coupling in glassy materials.

Conclusions:

  • Disordered glassy materials provide unique opportunities for controlling quantum phenomena.
  • Amorphous materials offer an effective alternative to crystalline solids for quantum material design.
  • The developed nanoprobes show potential for clinical translation.