[Best medical treatment of lower extremity arterial disease in 2018]

Area of Science:

• Vascular Medicine
• Cardiovascular Health
• Public Health

Background:

• Lower extremity artery disease (LEAD) is prevalent and leads to significant disability.
• LEAD is strongly linked to increased cardiovascular morbidity and mortality.
• Patients with LEAD face substantial functional limitations.

Purpose of the Study:

• To emphasize the critical role of optimal medical treatment in managing lower extremity artery disease.
• To highlight the comprehensive approach required for effective clinical management.
• To underscore the importance of risk factor control in LEAD patients.

Main Methods:

• Management of cardiovascular risk factors is central to treatment.
• Lifestyle modifications, including healthy living and physical activity, are key.
• Pharmacological interventions (antihypertensives, lipid-lowering, antidiabetics, antithrombotics) are essential when indicated.

Main Results:

• Optimal medical treatment significantly impacts patient outcomes.
• Comprehensive risk factor management reduces morbidity and mortality.
• Structured physical activity improves patient functioning.

Conclusions:

• Optimal medical treatment is fundamental for patients with lower extremity artery disease.
• Clinicians must prioritize risk factor management in all LEAD patients.
• A multi-faceted approach combining lifestyle and medication is crucial for effective care.