Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.7K
3.7K
Gene Flow02:39

Gene Flow

37.8K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
37.8K
C4 Pathway and CAM01:27

C4 Pathway and CAM

49.2K
Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
49.2K
Electric Potential and Potential Difference01:16

Electric Potential and Potential Difference

5.7K
Suppose a positive test charge moves away from a positive static charge, then the Coulomb force does positive work, and its electric potential energy decreases. The potential energy per unit charge is defined as the electric potential. The electric potential is independent of the test charge.
When a test charge moves from the initial to the final position, the electric potential difference between those positions is defined as the ratio of the change in the potential energy to the charge on the...
5.7K
Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

8.3K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
8.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction notice to "Effect of moisture content on greenhouse gas and NH<sub>3</sub> emissions from pig manure converted by black soldier fly" [Sci. Total Environ. 697 (2019) 133840].

The Science of the total environment·2026
Same author

Black Soldier Fly Can Safely Co-Convert Antibiotic Fermentation Residue and Potato Peel Waste into a Valuable Feed Resource.

Insects·2026
Same author

Coordination Compensation Stabilization of Monodentate-Ligand Copper-Iodide Hybrids for Efficient Light-Emitting Diodes With Record-High External Quantum Efficiency Above 20.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Engineering a gut synthetic microbial community to enhance protein bioconversion from organic wastes by black soldier fly larvae.

Bioresource technology·2026
Same author

Cyclin-Dependent Kinase 5 Contributes to Bruton's Tyrosine Kinase Inhibitor Resistance via the IRE1α/XBP1 Axis in Mantle Cell Lymphoma.

Research square·2026
Same author

High-performance red light-emitting diodes from quasi-two-dimensional perovskite nanocrystals.

Nature communications·2026

Related Experiment Video

Updated: Feb 1, 2026

Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies
05:51

Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies

Published on: June 18, 2020

3.5K

Distinct genes and pathways associated with transcriptome differences in early cardiac development between fast- and

Jibin Zhang1, Carl J Schmidt2, Susan J Lamont1

  • 1Department of Animal Science, Iowa State University, Ames, IA, United States of America.

Plos One
|December 6, 2018
PubMed
Summary

Fast-growing broilers experience heart dysfunction due to rapid growth. This study identified key genes and pathways, like lipid transport and cell cycle regulation, linked to imbalanced cardiac development in broilers, offering breeding targets.

More Related Videos

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae
10:18

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae

Published on: April 25, 2015

10.7K
Mining Spatial Transcriptomics Datasets using DeepSpaceDB
10:16

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

769

Related Experiment Videos

Last Updated: Feb 1, 2026

Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies
05:51

Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies

Published on: June 18, 2020

3.5K
A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae
10:18

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae

Published on: April 25, 2015

10.7K
Mining Spatial Transcriptomics Datasets using DeepSpaceDB
10:16

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

769

Area of Science:

  • Animal Science
  • Genomics
  • Cardiovascular Physiology

Background:

  • Modern fast-growing broilers exhibit cardiac dysfunction due to their hearts' inability to support rapid body mass increase.
  • Identifying genetic factors is crucial for improving broiler cardiac health through selective breeding.

Purpose of the Study:

  • To compare the left ventricular transcriptome between fast-growing (Ross 708) and heritage (Illinois) broiler lines.
  • To identify genes and pathways associated with compromised cardiac development in modern broilers.

Main Methods:

  • RNA-sequencing (RNA-seq) analysis of left ventricular tissue from Ross 708 and Illinois broilers at days 6 and 21 post-hatch.
  • Differential gene expression analysis and Ingenuity Pathway Analysis (IPA).

Main Results:

  • The number of differentially expressed genes (DEGs) increased with age, with Ross broilers showing more DEGs than Illinois broilers.
  • Significant changes in muscle and immune-related genes were observed in both lines.
  • Ross broilers displayed notable alterations in lipid transporter genes (APOA4, APOB, APOH, FABP4, RBP7).
  • IPA indicated increased apoptosis and inhibited cell cycles linked to lipid accumulation, oxidative stress, and endoplasmic reticulum stress in fast-growing broilers.

Conclusions:

  • Imbalanced cardiac development in fast-growing broilers is associated with altered lipid metabolism, oxidative stress, and endoplasmic reticulum stress.
  • Cell cycle regulatory pathways, such as 'Mitotic Roles of Polo-like Kinases,' are implicated in broiler cardiac apoptosis.
  • Findings provide potential genetic targets for enhancing cardiac health in broiler populations through breeding programs.