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Detection of intracellular Helicobacter pylori in Candida. SPP from neonate oral swabs

Lillian Matamala-Valdés1, Kimberly Sánchez-Alonzo1, Cristian Parra1

  • 1Universidad de Concepción, Víctor Lamas 1290, casilla 160 C, Concepción, Región del Biobío, Chile.

Revista Da Associacao Medica Brasileira (1992)
|December 6, 2018
PubMed

Insights

This study found Helicobacter pylori (H. pylori) living inside oral yeast in newborns. This confirms the bacteria

Area of Science:

  • Microbiology
  • Neonatal Health
  • Infectious Diseases

Background:

  • Emerging evidence suggests Helicobacter pylori (H. pylori) presence in newborns.
  • Previous studies indicated H. pylori in newborn stool and oral yeast.
  • Research confirming early-life H. pylori colonization is limited.

Purpose of the Study:

  • To detect intracellular H. pylori within oral yeasts in newborns.
  • To identify H. pylori antigens in meconium samples from newborns.

Main Methods:

  • Cross-sectional descriptive study involving oral swabs and meconium from infants.
  • Yeast identification using CHROMagar Candida, Germinal Tube Test, and API Candida System.
  • Microscopic and fluorescence analysis of yeasts, H. pylori antigen detection, and PCR for specific bacterial genes.

Main Results:

  • Intracellular H. pylori was successfully identified within Candida glabrata yeast.
  • The yeast was isolated from an oral swab sample of a newborn infant.
  • H. pylori antigen detection and PCR confirmed bacterial presence.

Conclusions:

  • This study provides evidence for the existence of intracellular H. pylori in newborns.
  • Findings suggest early-life colonization of H. pylori in the oral cavity.
  • Further research is warranted to understand the implications of neonatal H. pylori infection.
Abstract

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