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Updated: Feb 1, 2026

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Published on: October 8, 2013
Drug Targetor: a web interface to investigate the human druggome for over 500 phenotypes
Héléna A Gaspar1,2, Christopher Hübel1,2,3, Gerome Breen1,2
1Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry (SGDP) Centre, King's College London, London, UK.
Summary:
Results from hundreds of genome-wide association studies (GWAS) are now freely available and offer a catalogue of the association between phenotypes across medicine with variants in the genome. With the aim of using this data to better understand therapeutic mechanisms, we have developed Drug Targetor, a web interface that allows the generation and exploration of drug-target networks of hundreds of phenotypes using GWAS data. Drug Targetor networks consist of drug and target nodes ordered by genetic association and connected by drug-target or drug-gene relationship. We show that Drug Targetor can help prioritize drugs, targets and drug-target interactions for a specific phenotype based on genetic evidence.
Availability And Implementation:
Drug Targetor v1.21 is a web application freely available online at drugtargetor.com and under MIT licence. The source code can be found at https://github.com/hagax8/drugtargetor.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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