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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Cancer

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

What is Cancer?

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

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Related Experiment Video

Updated: Feb 1, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

Bioactive Nanoparticles for Cancer Immunotherapy.

Suchithra Poilil Surendran¹, Myeong Ju Moon², Rayoung Park³

¹Department of Biomedical Sciences, Biomolecular Theranostics (BiT) Lab, Chonnam National University Medical School, Hwasun 58128, South Korea. 9pssuchithra@gmail.com.

International Journal of Molecular Sciences

|December 7, 2018

Summary

Nanoparticle systems offer a promising future for cancer immunotherapy by delivering agents with high specificity and efficacy. This review explores current trends in using various nanoparticles for targeted cancer treatment.

Keywords:

PLGA nanoparticles bioactive nanoparticles cancer immunotherapy gold nanoparticles liposomes

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Area of Science:

Oncology
Nanotechnology
Immunology

Background:

Immunotherapy is a key cancer treatment strategy, with ongoing research spurred by recent advancements.
Targeting the tumor microenvironment and immune system is crucial for effective cancer therapy.
Nanoparticle systems are emerging as powerful tools for delivering immunotherapeutic agents.

Purpose of the Study:

To review current trends in nanoparticle-based cancer immunotherapy.
To evaluate the efficiency of nanosystems in delivering various immunotherapeutic agents.
To summarize available bioactive nanoparticle systems for cancer treatment.

Main Methods:

Review of current literature on nanoparticle systems in cancer immunotherapy.
Analysis of various nanoparticle types including PLGA, liposomes, micelles, gold, iron oxide, dendrimers, and artificial exosomes.
Examination of the role of nanoparticles in delivering antigens, adjuvants, and drugs.

Main Results:

Nanoparticles demonstrate high specificity, efficacy, and diagnostic/imaging capabilities for cancer therapy.
Various nanoparticle systems are effectively employed for delivering immunotherapeutic agents.
Combination therapy using nanoparticles shows enhanced tumor treatment potential.

Conclusions:

Nanoparticle-based immunotherapy represents a significant advancement in cancer treatment.
The specificity and multifaceted capabilities of nanoparticles enhance their therapeutic potential.
Further research into nanoparticle systems is vital for future cancer immunotherapy strategies.