Related Experiment Video
Updated: Feb 1, 2026
11:10
Atomic Layer Deposition of Vanadium Dioxide and a Temperature-dependent Optical Model
Published on: May 23, 2018
12.5K
Optimal control applied to a temperature dependent schistosomiasis model
Chester Kalinda1, Steady Mushayabasa2, Moses J Chimbari1
1College of Health Sciences, Howard Campus, University of KwaZulu-Natal, Durban 4041, South Africa.
Bio Systems
|December 7, 2018
Summary
Optimal control significantly reduces schistosomiasis burden by over threefold. Strategies vary with cost: low costs mean prolonged, maximum strength interventions, while high costs necessitate balanced, reduced strength application to manage infection.
Area of Science:
- Epidemiology
- Mathematical Biology
- Public Health
Background:
- Schistosomiasis is a prevalent water-borne disease, posing a significant global health challenge, particularly in endemic regions.
- Effective control strategies are crucial to mitigate the impact of schistosomiasis on human populations and travelers.
Purpose of the Study:
- To apply optimal control theory to a temperature-dependent schistosomiasis model.
- To identify cost-effective strategies for minimizing human infection and disease burden.
Main Methods:
- Development and analysis of a mathematical model incorporating temperature-dependent transmission dynamics.
- Application of optimal control techniques to determine intervention strategies.
Main Results:
- Optimal control can reduce the schistosomiasis burden by more than threefold.
- Low-cost optimal strategies involve prolonged, maximum-strength interventions.
- High-cost scenarios require reduced-strength interventions for a cost-benefit balance.
Conclusions:
- Optimal control theory provides a valuable framework for managing schistosomiasis.
- Cost-effectiveness is a key consideration in designing schistosomiasis control interventions.
- The study offers insights for minimizing infected hosts and vectors through strategic control.
Related Concept Videos
02:55Temperature Dependence on Reaction Rate
89.0K
The Collision Theory
Atoms, molecules, or ions must collide before they can react with each other. Atoms must be close together to form chemical bonds. This premise is the basis for a theory that explains many observations regarding chemical kinetics, including factors affecting reaction rates.
The collision theory is based on the postulates that (i) the reaction rate is proportional to the rate of reactant collisions, (ii) the reacting species collide in an orientation allowing contact between...
Atoms, molecules, or ions must collide before they can react with each other. Atoms must be close together to form chemical bonds. This premise is the basis for a theory that explains many observations regarding chemical kinetics, including factors affecting reaction rates.
The collision theory is based on the postulates that (i) the reaction rate is proportional to the rate of reactant collisions, (ii) the reacting species collide in an orientation allowing contact between...
89.0K
01:12Temperature Dependent Deformation
399
In a nonhomogeneous rod made up of steel and brass, restrained at both ends and subjected to a temperature change, several steps are involved in calculating the stress and compressive load. Due to the problem's static indeterminacy, one end support is disconnected, allowing the rod to experience the temperature change freely. Next, an unknown force is applied at the free end, triggering deformations in the rod's steel and brass portions. These deformations are then calculated and added...
399
01:23Physical Methods for Controlling Microbial Growth: Temperature
1.2K
Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
1.2K
02:11Effects of Temperature on Free Energy
28.3K
The spontaneity of a process depends upon the temperature of the system. Phase transitions, for example, will proceed spontaneously in one direction or the other depending upon the temperature of the substance in question. Likewise, some chemical reactions can also exhibit temperature-dependent spontaneities. To illustrate this concept, the equation relating free energy change to the enthalpy and entropy changes for the process is considered:
28.3K
01:21Frequency-dependent Selection
24.0K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
24.0K
00:48Optimal Foraging
13.8K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
13.8K