Tuning store-operated calcium entry to modulate Ca2+-dependent physiological processes

Hwei Ling Ong1, Krishna Prasad Subedi1, Ga-Yeon Son1

  • 1Secretory Physiology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.

Summary

This review details how stromal interaction molecules (STIM1/2) regulate calcium signaling via Orai1 and TRPC channels, crucial for cell functions. Understanding these calcium entry pathways is key to cellular regulation.

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