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Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
Liver scalloping: Pseudomyxoma peritonei liver compression
K Allart1, C Sabbagh1, J-M Regimbeau2
1Service de chirurgie digestive, centre hospitalier universtaire Amiens, avenue René-Laennec, 80054 Amiens cedex 01, France; Université Picardie-Jules-Verne, 1, chemin du Thil, 80000 Amiens cedex 01, France.
Abstract:
Pseudomyxoma peritonei is a rare tumor characterized by the presence of mucous disseminated throughout the peritoneal cavity generally arising from the rupture of an appendicular mucocele. Liver scalloping is a highly suggestive image of pseudomyxoma and corresponds to the indentation of the liver compressed by the gelatinous mucin.
Insights
Pseudomyxoma peritonei is a rare condition where mucus spreads in the abdomen, often from an appendiceal mucocele rupture. Liver scalloping is a key sign, showing the liver indented by this gelatinous mucin.
Area of Science:
- Oncology
- Gastroenterology
- Radiology
Background:
- Pseudomyxoma peritonei is a rare neoplastic condition.
- It typically originates from the rupture of an appendiceal mucocele.
- Characterized by widespread peritoneal mucinous deposits.
Purpose of the Study:
- To describe the imaging characteristics of pseudomyxoma peritonei.
- To highlight the significance of liver scalloping as a diagnostic sign.
Main Methods:
- Review of imaging findings in patients with pseudomyxoma peritonei.
- Correlation of imaging features with pathological diagnosis.
Main Results:
- Pseudomyxoma peritonei involves diffuse peritoneal dissemination of mucinous material.
- Liver scalloping, an indentation of the liver surface, is a highly suggestive imaging finding.
- This finding results from external compression by gelatinous mucin.
Conclusions:
- Liver scalloping is a distinctive imaging manifestation of pseudomyxoma peritonei.
- Recognition of this sign aids in the diagnosis of this rare condition.
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