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Updated: Feb 1, 2026

Assaying Locomotor Activity to Study Circadian Rhythms and Sleep Parameters in Drosophila
Published on: September 28, 2010
The emerging link between cancer, metabolism, and circadian rhythms
Selma Masri1, Paolo Sassone-Corsi2
1Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA. smasri@uci.edu.
Abstract:
The circadian clock is a complex cellular mechanism that, through the control of diverse metabolic and gene expression pathways, governs a large array of cyclic physiological processes. Epidemiological and clinical data reveal a connection between the disruption of circadian rhythms and cancer that is supported by recent preclinical data. In addition, results from animal models and molecular studies underscore emerging links between cancer metabolism and the circadian clock. This has implications for therapeutic approaches, and we discuss the possible design of chronopharmacological strategies.
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