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Large subcortical hemispheric infarctions. Presentation and prognosis.

R L Levine1, H L Lagreze, J A Dobkin

  • 1Department of Neurology, William S. Middleton Veterans Administration Hospital, Madison, WI 53705.

Archives of Neurology
|October 1, 1988
PubMed
Summary
This summary is machine-generated.

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This study identifies a specific stroke subtype characterized by severe limb weakness and cortical signs. Early identification and understanding of large subcortical hemispheric infarction are crucial for patient outcomes.

Area of Science:

  • Neurology
  • Radiology
  • Stroke Medicine

Background:

  • Large subcortical hemispheric infarction is a distinct stroke subtype.
  • Computed tomography (CT) aids in its identification.

Purpose of the Study:

  • To describe the clinical presentation and prognostic features of large subcortical hemispheric infarction.
  • To analyze stroke etiology and recurrence in this specific patient group.

Main Methods:

  • Retrospective analysis of stroke registry patients.
  • Inclusion of cases from prior literature reports.
  • Review of computed tomography findings and neurological examinations.

Main Results:

  • Identified 24 cases (1%) of large subcortical hemispheric infarction among 2198 stroke patients.

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  • Common symptoms included severe weakness (76%), aphasia/neglect (68%), and transient ischemic attacks (24%).
  • Large vessel occlusive disease (59%) and embolic occlusion (22%) were frequent causes.

    • Conclusions:

    • Large subcortical hemispheric infarction presents with a characteristic neurological profile.
    • Understanding this stroke subtype is vital for diagnosis and management.
    • Recurrent stroke or death occurred in 14% of patients during follow-up.