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Proteomics01:33

Proteomics

9.8K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

5.3K
Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
5.3K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

8.6K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
8.6K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

2.7K
Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.7K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

2.9K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
2.9K
Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

29.9K

Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
29.9K

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Related Experiment Video

Updated: Feb 1, 2026

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis
06:59

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis

Published on: August 11, 2010

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Advanced Proteomic Approaches to Elucidate Somatic Embryogenesis.

Victor Aguilar-Hernández1, Víctor M Loyola-Vargas2

  • 1Catedrático CONACYT, Unidad de Bioquímica y Biología Molecular de Plantas, Centro de Investigación Científica de Yucatán, Mérida, Mexico.

Frontiers in Plant Science
|December 8, 2018
PubMed
Summary

Somatic embryogenesis (SE) research uses proteomics to understand how somatic cells transform into embryonic cells. This approach reveals key proteins and pathways, advancing crop improvement and conservation technologies.

Keywords:
2D electrophoresisdifferentiationplant growth regulatorsproteomicssomatic embryogenesis

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Area of Science:

  • Plant Biotechnology
  • Developmental Biology
  • Proteomics

Background:

  • Somatic embryogenesis (SE) is a crucial plant development process where somatic cells form embryos.
  • SE applications include genetic transformation, conservation, and synthetic seed production.
  • Transcriptome data suggests complex protein networks regulate somatic cell fate during SE.

Purpose of the Study:

  • To review progress in SE research using proteomic data.
  • To focus on protein expression changes during somatic embryo development.
  • To highlight the potential of new quantitative proteomics in understanding SE induction.

Main Methods:

  • Analysis of proteomic data from various SE stages.
  • Comparison of protein abundance changes during somatic embryo induction.
  • Review of advanced proteomic techniques for SE research.

Main Results:

  • Proteomic studies reveal intricate protein networks governing somatic cell fate.
  • Quantitative proteomics offers new insights into SE induction pathways.
  • Understanding protein dynamics is key to deciphering SE mechanisms.

Conclusions:

  • Proteomics is vital for identifying critical proteins in SE.
  • Further research using proteomics will elucidate protein localization, modifications, and turnover.
  • This knowledge will drive biotechnological strategies for efficient crop production.