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Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
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Tranexamic acid therapy for postoperative bleeding after bariatric surgery.
R A Klaassen1, C A Selles1, J W van den Berg1
11Department of Surgery, Maasstad Hospital, Maasstadweg 21, 3079 DZ Rotterdam, The Netherlands.
BMC Obesity
|December 8, 2018
Summary
Tranexamic acid effectively reduces reoperation rates for bleeding after bariatric surgery. This study found no associated thrombo-embolic complications, suggesting a safe and beneficial treatment option.
Area of Science:
- Bariatric Surgery
- Surgical Hemorrhage Management
Background:
- Postoperative bleeding from enteric staple lines is a known complication of bariatric surgery.
- Reoperation for hemostasis is sometimes necessary, occurring in up to 2.5% of cases.
- Conservative therapy with tranexamic acid for postoperative hemorrhage is a novel approach.
Purpose of the Study:
- To evaluate the efficacy of tranexamic acid in reducing reoperation rates for postoperative bleeding after bariatric surgery.
- To assess the rate of thrombo-embolic complications associated with tranexamic acid use in this patient population.
Main Methods:
- Retrospective review of 1388 patients undergoing bariatric surgery (gastric bypass or sleeve gastrectomy).
- Analysis of tranexamic acid administration, reoperation rates, transfusion rates, and thrombo-embolic complications.
Main Results:
- Significant hemorrhage occurred in 3.2% of patients (45/1388).
- Tranexamic acid was administered to 44 patients, with treatment failure in 4 cases.
- The overall reoperation rate was 0.4%, and no thrombo-embolic complications were observed.
Conclusions:
- Tranexamic acid administration appears safe and effective in reducing the need for reoperation due to bleeding after bariatric procedures.
- The findings support tranexamic acid as a valuable tool for managing postoperative hemorrhage in bariatric surgery.
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