[B-lymphocytes in multiple sclerosis: studies concerning their levels in the blood and cerebrospinal fluid]

In this paper the B lymphocyte population was investigated by fluoresceinated immunoglobulin assay in peripheral blood and cerebrospinal fluid (CSF) in M.S. patients and other neurological diseases taken as control. In peripheral blood there was no significant difference in two groups considered. In CSF there was a higher percentage of B-cells only in M.S. patients. This datum was more evident when the percentage of B cells was simultaneously determined in CSF and blood. It can be hypothesized the existence of subpopulations of B cells synthesizing Ig in the CST.