Related Experiment Videos
Posterior polymorphous keratopathy.
The British Journal of Ophthalmology
|January 1, 1978
Summary
Posterior polymorphous keratopathy (PPK) can be congenital or acquired, with congenital cases linked to mesodermal dysplasia. Over half of PPK cases are progressive, often requiring corneal transplant surgery.
Area of Science:
- Ophthalmology
- Pathology
Background:
- Posterior polymorphous changes of the cornea present diagnostic challenges.
- Understanding the etiology and progression is crucial for patient management.
Observation:
- Seven cases of posterior polymorphous corneal changes were clinically and pathologically examined.
- Literature review was conducted to contextualize findings.
Findings:
- Posterior polymorphous keratopathy (PPK) encompasses both congenital (familial/sporadic) and acquired forms.
- Congenital PPK is a mild mesodermal dysplasia; acquired PPK results from local disease.
- While some PPK cases are static, over 50% exhibit slow progression.
Implications:
- The term 'posterior polymorphous keratopathy' is recommended over 'posterior polymorphous dystrophy'.
- Progressive PPK necessitates consideration of penetrating keratoplasty.
- Distinguishing between congenital and acquired forms aids in prognosis and treatment planning.