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Updated: Feb 1, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Two new abietane diterpenoids from the leaves of Rabdosia serra
Gui-Lian Liu1, Wei Xu1, Xin-Juan Liu1
1Department of Science and Education, Pingxiang People's Hospital of Southern Medical University, Pingxiang, Jiangxi 337055, China.
Abstract:
Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3-6). Their structures were determined by spectroscopic data. Compound 1 represented the rare examples of abietane diterpenoids featuring a 16-methoxycarbonyl group.
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In general, in a nucleophilic substitution reaction, a nucleophile displaces a functional group, called the leaving group, from the substrate to give a substituted product. A leaving group departs the substrate molecule through heterolytic cleavage, taking the pair of electrons with it to become a relatively stable weak base in the form of an anion or a neutral molecule.
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