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Updated: Feb 1, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Synthesis-guided structure revision of the monoterpene alcohol isolated from Mentha haplocalyx
Shunsuke Konishi1,2, Naoki Mori1, Hirosato Takikawa1
1a Department of Applied Biological Chemistry , Graduate School of Agricultural and Life Sciences, The University of Tokyo , Tokyo , Japan.
Abstract:
The monoterpene isolated from Mentha haplocalyx, 3,3,5-trimethyl-2-oxabicyclo[2.2.2]oct-5-en-4-ol, was synthesized according to its proposed structure. However, the NMR data of the synthetic sample were not in agreement with those reported for the natural product. After considerable efforts, the genuine structure was confirmed as (1R*,2R*)-4-(1'-hydroxy-1'-methylethyl)-1-methylycyclohex-3-ene-1,2-diol.
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