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Multiple evanescent white dot syndrome following rabies vaccination: a case report
Jia-Song Yang1, Chun-Li Chen2,3, Yu-Zhang Hu4
1Department of Ophthalmology, Apex Eye Hospital, Henan Province, China.
Background:
To report a case of multiple evanescent white dot syndrome (MEWDS) following simultaneous rabies vaccination.
Case Presentation:
Review of the clinical, laboratory, photographic, optical coherence tomographic (OCT), fundus autofluorescent, angiographic, electrophysiologic, and perimetric records of a patient suffering from MEWDS.
Results:
A healthy 33-year-old Chinese female suffering from rapidly progressive visual loss of her left eye associated with photopsia and a para-central scotoma, seven days after receiving simultaneous rabies vaccination. Both anterior segments and fundus examination were unremarkable. The findings on OCT, electrophysiology, and perimetry were pathognomonic for MEWDS.
Conclusions:
The clinical presentation and the benign course were consistent with the diagnosis of MEWDS. No other events could be identified as a cause, other than the rabies vaccination. This case may suggest an autoimmune basis for MEWDS in predisposed patients.
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