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Guidelines for Elective Pediatric Fiberoptic Intubation
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Pediatric forms of vasculitis.

Seza Özen1, Hafize Emine Sönmez1, Selcan Demir1

  • 1Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Best Practice & Research. Clinical Rheumatology
|December 12, 2018
PubMed
Summary
This summary is machine-generated.

Childhood vasculitides are complex disorders impacting multiple body systems. This review highlights key differences between pediatric and adult vasculitis, including monogenic forms like DADA2 and HA20.

Keywords:
Childhood vasculitidesClassificationManagementPrimary vasculitides

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Area of Science:

  • Pediatric Rheumatology
  • Immunology
  • Genetics

Background:

  • Childhood vasculitides are complex, potentially severe systemic inflammatory disorders.
  • Recent advances include classification criteria and outcome measures for pediatric vasculitis.
  • Significant differences exist between childhood and adult vasculitis presentations and management.

Purpose of the Study:

  • To review childhood vasculitides.
  • To emphasize distinctions between pediatric and adult vasculitis.
  • To discuss monogenic vasculitides like DADA2 and HA20.

Main Methods:

  • Literature review focusing on pediatric vasculitis.
  • Comparative analysis of childhood versus adult vasculitis.
  • Inclusion of monogenic forms of vasculitis.

Main Results:

  • Childhood vasculitides present unique challenges and affect various organ systems.
  • Advances in classification and assessment are improving pediatric care.
  • Monogenic forms like DADA2 and HA20 represent distinct etiological categories.

Conclusions:

  • Understanding pediatric vasculitis requires recognizing its unique features compared to adult forms.
  • Classification criteria and outcome assessments are crucial for managing childhood vasculitis.
  • Monogenic disorders are increasingly recognized as important causes of vasculitis in children.