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Schemas

Schemas

A schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.

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Related Experiment Video

Updated: Feb 1, 2026

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

[Melanoma update].

C Longvert¹, P Saiag¹

¹Service de dermatologie, EA4340 biomarqueurs en cancérologie et onco-hématologie, UVSQ, université Paris-Saclay, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92104 Boulogne-Billancourt cedex, France.

La Revue De Medecine Interne

|December 12, 2018

Summary

This summary is machine-generated.

Malignant melanoma treatment has advanced significantly since 2011 with new immunotherapies and targeted therapies, improving survival for advanced stages. Research continues to enhance efficacy and identify biomarkers for better outcomes.

Keywords:

Immunotherapy Immunothérapie Melanoma Mélanome Targeted therapy Thérapie ciblée

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Last Updated: Feb 1, 2026

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

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A Melanoma Patient-Derived Xenograft Model

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Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

Published on: January 25, 2015

Area of Science:

Oncology
Immunology
Dermatology

Background:

Malignant melanoma incidence has risen since the 1980s.
Advanced melanoma historically had a poor prognosis due to high metastatic potential.
Loco-regional melanoma is best treated with surgery.

Purpose of the Study:

To review recent advancements in metastatic melanoma treatment.
To highlight the impact of molecular and immunological insights.
To discuss ongoing research for improved therapeutic strategies.

Main Methods:

Review of systemic therapeutic agents including immunotherapies and targeted therapies.
Analysis of clinical outcomes and survival data.
Discussion of current research in predictive biomarkers and combination therapies.

Main Results:

Significant improvement in overall survival for advanced melanoma since 2011, with some patients achieving long-term survival.
Introduction of immunological checkpoint inhibitors and BRAF/MEK inhibitors has revolutionized treatment.
Efficacy demonstrated in the adjuvant setting for high-risk melanoma.

Conclusions:

Recent therapeutic advances offer hope for curing some metastatic melanoma cases.
Further research is crucial to overcome treatment resistance and improve response rates.
Adjuvant therapies are expected to become widely available soon.