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Published on: October 25, 2016
Major complications of jejunal feeding in children
Conor McCann1, Paul S Cullis1, Amanda J McCabe1
1Department of Paediatric Surgery, Royal Hospital for Sick Children, Edinburgh, UK.
Insights
Jejunal feeding can lead to serious gastrointestinal complications, including bowel ischemia, intussusception, and volvulus, particularly in fragile, neurologically impaired children. These risks necessitate careful patient selection and informed consent.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Outcomes Research
Background:
- Direct jejunal feeding is utilized for nutritional support in pediatric patients with complex gastrointestinal issues.
- Potential complications associated with jejunal feeding require thorough investigation to ensure patient safety.
Purpose of the Study:
- To identify and characterize major gastrointestinal complications arising from direct jejunal feeding in a pediatric population.
- To hypothesize the potential for life-threatening surgical complications in a subset of patients receiving jejunal feeding.
Main Methods:
- Retrospective analysis of 197 pediatric patients who received jejunal feeding between 2008 and 2018.
- Data collection included patient demographics, comorbidities, feeding methods, and adverse events, with complications graded by Clavien-Dindo criteria (≥ IIIb).
- Study design classified as Level IV prognosis.
Main Results:
- 14 significant gastrointestinal complications occurred in 12 patients, with 11 classified as major (Clavien-Dindo grade > IIIb).
- Complications included non-mechanical bowel ischemia (n=7), intussusception (n=4), and volvulus (n=3), leading to bowel resections in 8 patients and 2 deaths.
- Neurologically impaired children constituted the majority (122/197) of patients receiving jejunal feeding.
Conclusions:
- Jejunal feeding is associated with a significant, underreported risk of major gastrointestinal compromise, including a 6.1% risk of major surgical complications.
- A notable 3.6% of patients experienced bowel ischemia of unknown etiology, highlighting a critical risk factor.
- Comorbid, fragile, and neurologically impaired children are particularly susceptible, underscoring the need for comprehensive parental counseling and informed consent prior to initiating jejunal feeding.
Aim Of The Study:
The aim of the study was to identify major gastrointestinal complications associated with direct jejunal feeding. We hypothesized that jejunal feeding may cause life-threatening surgical complications in a minority of patients.
Methods:
All patients undergoing jejunal feeding between 1/2008 and 1/2018 at a pediatric surgical unit were identified retrospectively. Data sought from records included demographics, comorbidities, indications, feeding strategies, adverse events, and follow-up. Major surgical complications were defined by Clavien-Dindo grade ≥ IIIb and involving the GI tract (excluding changes of jejunal tube).
Main Results:
197 patients were identified (110 female). Median age (IQR) at initiation of jejunal feeding months was 5.6 (6-164) months. 122 were neurologically impaired. The most frequent indications were: GERD/gastroparesis (n = 114), prophylaxis/treatment of Superior Mesenteric Artery (SMA) syndrome (N.B. our center is a national spinal deformity unit) (n = 47), congenital anomalies of aerodigestive anatomy (n = 17), and malignancy (n = 7). 125 patients were managed with nasojejunal feeding alone: gastrojejunal tube (n = 51) and via Roux-en-Y jejunostomy (n = 21). There were 14 significant gastrointestinal complications (n = 11 grade > IIIb) identified among 12 patients, of whom 8 required bowel resections, and 2 died as a result: nonmechanical bowel ischemia (n = 7), intussusception (n = 4), and volvulus (n = 3).
Conclusion:
This series highlights the major complications of jejunal feeding, including a significant yet underreported risk of gut compromise. Patients undergoing jejunal feeding had a 6.1% risk of developing major surgical complications (of note, 3.6% developed bowel ischemia of unknown etiology). Susceptible children were comorbid, fragile, and neurologically impaired. These findings should influence parental discussions and informed consent before embarking upon jejunal feeding.
Level Of Evidence:
Level IV prognosis study.
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