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Updated: Feb 1, 2026

Assessing Disaster Resilience of Concrete with Titanium Dioxide Nanoparticles
Published on: November 14, 2025
Titanium dioxide and modified titanium dioxide by silver nanoparticles as an anti biofilm filler content for
Hércules Bezerra Dias1, Maria Inês Basso Bernardi2, Taís Maria Bauab3
1Department of Restorative Dentistry, Araraquara School of Dentistry, University of São Paulo State - UNESP, Araraquara, SP 14801-903, Brazil.
Objective:
The aim of this study was to evaluate the antibacterial activity of a composite resin modified by TiO2 and TiO2/Ag nanoparticles and their influence over different properties.
Methods:
TiO2 and TiO2/Ag NPs were synthesized by polymeric precursor and microwave-assisted hydrothermal methods and then, characterized by different techniques. Direct contact test was performed using Filtek™ Z350XT blended with 0.5; 1 and 2% (wt.) of NPs against Streptococcus mutans to determine the best concentration to the other tests. After that, the modified composite resin was tested against S. mutans 7-day biofilm (CFU/mL). Also, compressive and diametral tensile strength (n=40), degree of conversion (n=25) and surface roughness (n=50) was performed. The data were analyzed by ANOVA and Tukey's test for multiple comparison at 5% significance level.
Results:
The direct contact test demonstrates that by increasing the nanoparticle content, the bacterial growth is significantly reduceed (p<0.05). The inclusion of 2% of TiO2/Ag NPs significantly decreased (p<0.05) the biofilm accumulation of S. mutans on the composite resin surface compared to the control Group. The TiO2 NPs treated with an organosilane increased compressive strength of composite resin (p<0.05). Degree of conversion remained unchanged (p>0.05) and the surface roughness increased with the NPs (p<0.05), except for the TiO2 by polymeric precursor Group (p>0.05).
Significance:
The development of an antibacterial dental restorative material that hinder S. mutans biofilm without sacrificing the mechanical and physical properties is desirable in dental material science.
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