Incidence and effect of early postoperative ventricular arrhythmias after congenital heart surgery

Sarah R Fuchs1, Andrew H Smith2, Sara L Van Driest3

  • 1Department of Pediatrics, Thomas P. Graham Jr. Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee.

Heart Rhythm
|December 12, 2018
PubMed

Insights

Postoperative ventricular arrhythmias (VAs) after pediatric congenital heart disease (CHD) surgery are common and linked to higher mortality. Treated VAs are an independent risk factor for in-hospital death in these patients.

Area of Science:

  • Cardiology
  • Pediatric Surgery
  • Critical Care Medicine

Background:

  • Postoperative arrhythmias are a significant cause of morbidity and mortality in pediatric congenital heart disease (CHD) surgery.
  • A comprehensive evaluation of early postoperative ventricular arrhythmias (VAs) following CHD surgery has been lacking.

Purpose of the Study:

  • To determine the incidence of in-hospital VAs after CHD surgery.
  • To assess the clinical relevance and impact of VAs on postoperative outcomes.

Main Methods:

  • Prospective enrollment of patients undergoing CHD surgery from September 2007 to December 2016.
  • Univariate and multivariate analyses were employed to evaluate associations.
  • Adjustments were made for extracorporeal membrane oxygenation and stage 1 single ventricle palliation operations.

Main Results:

  • 18.5% of 2503 postoperative courses experienced VAs; 29.1% required treatment.
  • Monomorphic ventricular tachycardia was the most frequent treated VA (TVA).
  • TVAs were associated with increased need for extracorporeal membrane oxygenation (13.3% vs 5.5%) and higher in-hospital mortality (14.9% vs 4.0%).

Conclusions:

  • Early postoperative VAs after CHD surgery are more frequent than previously recognized.
  • Postoperative VAs are linked to increased in-hospital mortality.
  • Treated VAs independently predict in-hospital mortality in pediatric CHD surgery patients.
Abstract

Related Concept Videos

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
564
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
827
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.9K
Anatomy of the Heart01:27

Anatomy of the Heart

The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
119.8K
Anatomy of the Heart01:20

Anatomy of the Heart

The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
3.1K
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
1.9K