Incidence and effect of early postoperative ventricular arrhythmias after congenital heart surgery
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Updated: Feb 1, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Sarah R Fuchs1, Andrew H Smith2, Sara L Van Driest3
1Department of Pediatrics, Thomas P. Graham Jr. Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Insights
Postoperative ventricular arrhythmias (VAs) after pediatric congenital heart disease (CHD) surgery are common and linked to higher mortality. Treated VAs are an independent risk factor for in-hospital death in these patients.
Area of Science:
- Cardiology
- Pediatric Surgery
- Critical Care Medicine
Background:
- Postoperative arrhythmias are a significant cause of morbidity and mortality in pediatric congenital heart disease (CHD) surgery.
- A comprehensive evaluation of early postoperative ventricular arrhythmias (VAs) following CHD surgery has been lacking.
Purpose of the Study:
- To determine the incidence of in-hospital VAs after CHD surgery.
- To assess the clinical relevance and impact of VAs on postoperative outcomes.
Main Methods:
- Prospective enrollment of patients undergoing CHD surgery from September 2007 to December 2016.
- Univariate and multivariate analyses were employed to evaluate associations.
- Adjustments were made for extracorporeal membrane oxygenation and stage 1 single ventricle palliation operations.
Main Results:
- 18.5% of 2503 postoperative courses experienced VAs; 29.1% required treatment.
- Monomorphic ventricular tachycardia was the most frequent treated VA (TVA).
- TVAs were associated with increased need for extracorporeal membrane oxygenation (13.3% vs 5.5%) and higher in-hospital mortality (14.9% vs 4.0%).
Conclusions:
- Early postoperative VAs after CHD surgery are more frequent than previously recognized.
- Postoperative VAs are linked to increased in-hospital mortality.
- Treated VAs independently predict in-hospital mortality in pediatric CHD surgery patients.
Background:
Postoperative arrhythmias after pediatric congenital heart disease (CHD) surgery are a known cause of morbidity and are associated with mortality. A comprehensive evaluation of early postoperative ventricular arrhythmias (VAs) after CHD surgery has not been reported.
Objectives:
We sought to determine the incidence of in-hospital VAs after CHD surgery and assess the clinical relevance of this arrhythmia during the postoperative hospital course.
Methods:
Patients undergoing CHD surgery at our center from September 2007 through December 2016 were prospectively enrolled. Univariate and multivariate analysis was used to assess the association between postoperative VAs and in-hospital mortality, adjusting for postoperative extracorporeal membrane oxygenation and stage 1 single ventricle palliation operations.
Results:
A total of 2503 postoperative courses in 1835 patients were included. In all, 464 (18.5%) had VAs, of whom 135 (29.1%) received treatment. Monomorphic ventricular tachycardia was the most frequently treated ventricular arrhythmia (TVA; n=91 [62.3%]). TVAs were associated with increased postoperative extracorporeal membrane oxygenation (13.3% vs 5.5%; P < .001) and in-hospital mortality (14.9% vs 4.0%; P < .001). In multivariate analysis, TVA was an independent risk factor for in-hospital mortality (adjusted odds ratio 2.44; 95% confidence interval 1.21-4.92).
Conclusion:
Early postoperative VAs after CHD surgery are more common than previously reported. Postoperative VAs are associated with increased in-hospital mortality, and the subgroup of TVAs is an independent risk factor for in-hospital mortality.
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