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New stimulant formulations for pediatric attention-deficit/hyperactivity disorder: a case-based approach for the
Paige I Partain1, Jacob White, Paul Hammerness
1Department of Psychiatry, Boston Children's Hospital, Boston, Massachusetts, USA and Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
Purpose Of Review:
To provide an up-to-date clinical review of U.S. Food and Drug Administration (FDA)-approved stimulant medications for attention-deficit/hyperactivity disorder (ADHD), including a framework for individualized treatment by primary care pediatric providers.
Recent Findings:
Stimulant medications are first-line agents for pediatric ADHD. Since 2012, 11 novel stimulant medications have been approved by the FDA for the treatment of ADHD. Because of an expanded formulary of available methylphenidate-based and amphetamine-based stimulants, primary care providers may be unfamiliar with some novel medications outside a select formulary.
Summary:
The current broad formulary of methylphenidate-based and amphetamine-based stimulants provides primary care clinicians with a greater opportunity for personalized medicine within the patient-centered medical home. Through a systematic review of prior relevant medication trials, a consideration of daily symptom burden and thoughtful pragmatics, primary care providers can offer a more precise, customized stimulant treatment.
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