Related Experiment Video
Updated: Feb 1, 2026

Cerebrospinal Fluid MicroRNA Profiling Using Quantitative Real Time PCR
Published on: January 22, 2014
Cerebrospinal fluid HIV-1 escape according to different thresholds and underlying comorbidities: is it time to assess
Mattia Trunfio1, Carmela Pinnetti2, Emanuele Focà3
1Unit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino.
Abstract:
: No consensus has been reached on how to define cerebrospinal fluid HIV-1 escape (CSF-E). We describe its prevalence in 1095 paired CSF-plasma HIV-RNA measurements from antiretroviral-treated patients according to several definitions and neurological affections. CSF-E prevalence varied substantially (9.0-38.9%) and was higher in patients with cerebrovascular disorders, HIV-associated dementia and white matter abnormalities. Considering the variability in HIV-RNA quantification assays, the biological relevance of viral escape at different thresholds needs to be accurately assessed.
Related Concept Videos
Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain....
Escape Velocity
To calculate the escape velocity, it is assumed that no energy is lost to any frictional forces. In practice, a satellite...
Escape Velocities of Gases
Definite Integral
Definition of z-Transform
Properties of Definite Integral I

