Minimal change disease: A case report

Fay M Mitchell-Brown1, Tiernan Veisze

  • 1At California State University, Chico, Fay Mitchell-Brown is an associate professor and Tiernan Veisze is a senior nursing student. Dr. Mitchell-Brown teaches pathophysiology and is a practicing critical care nurse.

Nursing
|December 12, 2018
PubMed

Insights

Minimal change disease (MCD) is rare in adults but causes nephrotic syndrome. Early diagnosis and treatment of adult MCD are crucial for a positive patient outcome.

Area of Science:

  • Nephrology
  • Internal Medicine
  • Pediatric Nephrology

Background:

  • Minimal change disease (MCD) is a leading cause of nephrotic syndrome in children.
  • MCD is less frequently diagnosed in adult populations.
  • The condition involves glomerular damage leading to significant proteinuria.

Observation:

  • This article focuses on the diagnostic and therapeutic management of an adult patient with MCD.
  • It also details the essential nursing care considerations for this demographic.
  • The clinical presentation and pathological mechanisms of MCD are reviewed.

Findings:

  • Early recognition of MCD in adults is critical for effective management.
  • Prompt treatment initiation significantly improves patient prognosis.
  • Comprehensive nursing care is integral to the recovery process.

Implications:

  • Understanding adult MCD presentation aids in timely diagnosis and intervention.
  • Effective treatment strategies can prevent long-term renal complications.
  • Highlighting nursing care underscores its role in optimizing patient outcomes and recovery.

Related Concept Videos

Le Chatelier's Principle: Changing Temperature02:19

Le Chatelier's Principle: Changing Temperature

Consistent with the law of mass action, an equilibrium stressed by a change in concentration will shift to re-establish equilibrium without any change in the value of the equilibrium constant, K. When an equilibrium shifts in response to a temperature change, however, it is re-established with a different relative composition that exhibits a different value for the equilibrium constant.
To understand this phenomenon, consider the elementary reaction:
35.4K
Le Chatelier's Principle: Changing Concentration02:27

Le Chatelier's Principle: Changing Concentration

A system at equilibrium is in a state of dynamic balance, with forward and reverse reactions taking place at equal rates. If an equilibrium system is subjected to a change in conditions that affects these reaction rates differently (a stress), then the rates are no longer equal and the system is not at equilibrium. The system will subsequently experience a net reaction in the direction of a greater rate (a shift) that will re-establish the equilibrium. This phenomenon is summarized by Le...
65.8K
Global Climate Change01:50

Global Climate Change

Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
28.9K
Net Change Theorem01:22

Net Change Theorem

The Net Change Theorem is a fundamental principle in calculus that establishes a direct relationship between a function’s rate of change and its accumulated change over an interval. Mathematically, it states that the definite integral of a function's derivative over a given interval [a,b] yields the net change in the original function:This theorem has significant applications in various real-world scenarios, including physics, economics, and engineering. A particularly useful application...
70
Rates of Change01:20

Rates of Change

The rate of change is a central concept in mathematics that quantifies how one variable varies in response to another. It serves as a foundational tool in modeling dynamic systems across disciplines such as physics, biology, economics, and engineering. Understanding both average and instantaneous rates of change enables the analysis of behavior in functions that describe real-world phenomena.Average Rate of ChangeFor a function f(x) defined over an interval [x1,x2], the average rate of change...
93
Work Done During Volume Change01:17

Work Done During Volume Change

In mechanics, work is done on an object when the force acting on it displaces the object. In thermodynamics, work done on a system can be estimated when the system's volume changes during any thermodynamic process.
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
5.2K