Related Experiment Video
Updated: Feb 1, 2026

Endotoxin Activity Assay for the Detection of Whole Blood Endotoxemia in Critically Ill Patients
Published on: June 24, 2019
Comparison between invasive and noninvasive blood pressure measurements in critically ill patients receiving
Babandeep Kaur1, Sukhpal Kaur1, Lakshmi N Yaddanapudi2
1National Institute of Nursing Education.
Objective:
The aim of this study was to compare invasive and noninvasive monitoring of blood pressure (BP) in patients on inotropes.
Settings And Design:
This study was carried out in the ICU of a tertiary care centre. The design was comparative analytical.
Patients And Methods:
Thirty-six adult patients receiving inotropes with invasive arterial BP monitoring were studied. Systolic and diastolic BPs were recorded simultaneously using invasive (radial arterial cannula) and noninvasive (Philips Intellivue MP-60 oscillometric monitor attached to the opposite arm) methods every 30 min.
Statistical Analysis:
Agreement (precision) between both the methods was assessed using Bland-Altman analysis. A difference of more than 10 mmHg was considered clinically unacceptable. Linear regression of difference with invasive BP and analysis of variance with Tukey's correction of difference with the number of inotropes were carried out.
Results:
Overall, 1400 pairs of systolic and diastolic BP measurements were obtained. Systolic and diastolic pressures showed a difference of 2.3±16.9 and 0.7±10.6 mmHg, respectively. In all, 93.4% of systolic and 98.6% of diastolic pressure measurements were within the limits of agreement. The difference was clinically acceptable in 54.2% of measurements of systolic and 74.1% of diastolic measurements. Both systolic and diastolic BP differences were correlated with the number of inotropes that the patient was receiving.
Conclusion:
Noninvasive BP measurement using an oscilllometric monitor (Philips Intellivue MP-60) is not a reliable alternative to invasive intra-arterial measurement in patients receiving inotropes. The observed difference increased with the number of inotropes that the patient was receiving.
Related Concept Videos
Measurement of Blood Pressure
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Blood Pressure
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
Definition and Measurement of Pressure: Atmospheric Pressure, Barometer, and Manometer

