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Updated: Feb 1, 2026

Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue
Published on: January 19, 2019
An unique case suffering from repetitive syncope episodes due to ictal asystole
Ignacio Gil-Ortega1, Beatriz Garrido-Corro2, Milagros Gil-Ortega3
1Arrhythmia Unit, Service of Cardiology, Hospital Universitario Santa Maria del Rosell, Cartagena, Murcia, Spain.
Abstract:
We present the case of a patient with syncope with repetition over 12 years, with a clinical profile not clearly related with a cardiogenic origin, who was studied by several medical specialties without any accurate diagnosis. After subcutaneous loop recorder implantation, we were able to demonstrate how seizures acted as a trigger in the genesis of an exaggerated cardio inhibitory reflex. A new entity has been described, known as "ictal asystole", in patients with focal epilepsy mostly from the temporal lobes and has been implicated as a cardiac cause of sudden unexplained death in epilepsy. We think this case could add new information about some patients who are at high risk of death but they are misdiagnosed.
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