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Published on: April 13, 2015
Recurrence of Takotsubo cardiomyopathy with coronary slow flow phenomenon
Tomotake Tokunou1,2, Kenji Sadamatsu1
1Department of Cardiology, Saga Prefectural Hospital Koseikan, 1-12-9 Mizugae, Saga, Japan.
Abstract:
This report presents the case of a 54-year-old female with Takotsubo cardiomyopathy that recurred 12 years after the first episode. The coronary angiography at the first admission revealed ergonovine-induced coronary vasoconstriction in the left coronary artery, and recurrence recurred after the interruption of vasodilator therapy to prevent vasospasm. In addition, the coronary angiography both in the first and second event demonstrated coronary slow flow phenomenon, which improved after the intracoronary administration of nicorandil. These findings indicate that coronary microvascular constriction plays an important role in the pathophysiology of Takotsubo cardiomyopathy.
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